How Clinicians Use Therapeutic Drug Monitoring
نویسندگان
چکیده
منابع مشابه
Use of saliva in therapeutic drug monitoring.
We measured the concentrations of phenobarbital, phenytoin, primidone, ethosuximide, antipyrine, and caffeine in paired samples of saliva and plasma by gas chromatograph-mass spectrometer-computer (GC/MS/COM) and enzyme immunoassay. Mixed saliva was collected for the antipyrine and caffeine studies, parotid saliva for the phenobarbital, primidone, ethosuximide and phenytoin studies. The saliva/...
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1. Reinshagen M, Schutz E, Armstrong VW, Behrens C, von Tirpitz C, Stallmach A, et al. 6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active Crohn disease: results from a randomized, controlled, open trial. Clin Chem 2007;53:1306–14. 2. Shipkova M, Armstrong VW, Wieland E, Oellerich M. Differences in nucleotide hydr...
متن کاملAntifungal therapeutic drug monitoring: when, how, and why.
In recent years, the incidence of invasive fungal infections (IFI) has risen in parallel with a growing population of patients immunosuppressed as a consequence of different conditions, such as HIV infection, increasingly aggressive surgical techniques, solid organ and hematopoietic transplantations, illness severity of critically ill patients and, in a lower rate, anti-TNF therapies.1–3 In spi...
متن کاملA Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs
Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...
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ژورنال
عنوان ژورنال: Laboratory Medicine
سال: 1997
ISSN: 0007-5027,1943-7730
DOI: 10.1093/labmed/28.8.524